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Conditions/Rheumatoid arthritis
Condition 01 · Autoimmune · Joints

Rheumatoid arthritis

An immune system that has begun attacking the lining of the joints. Treated early, the damage can largely be prevented, which is why we would rather see you sooner with a maybe than later with a certainty.

Reviewed by Mark Jaffe, MD · Board certified rheumatologist

Original illustration: two mirrored joints
Mark 01   Two joints, mirrored. RA tends to strike both sides of the body at once.
01  Where it shows up

Small joints of the hands and feet, usually on both sides

02  The telltale sign

Morning stiffness that lasts more than an hour

03  Why timing matters

Joint damage is largely preventable when treatment starts early

04  Who you will see

Dr. Jaffe, with Elizabeth for follow up and infusions

Overview

Rheumatoid arthritis is an autoimmune disease. The immune system, which should protect you, starts to attack the synovium, the thin lining inside the joints. The lining swells, the joint becomes painful and stiff, and over time the cartilage and bone can be damaged.

It can begin at any age and is more common in women. It is a lifelong condition, but with modern treatment most people keep working, moving and doing what they love.

Older hands resting on a cane
Fig. 02   The hands are usually where it starts, and where early treatment protects the most.

Signs and symptoms

  • Swelling and tenderness in several joints, often the knuckles, wrists and the balls of the feet
  • Stiffness on waking that lasts more than an hour
  • Symptoms on both sides of the body at the same time
  • Fatigue and a general sense of being unwell
  • Firm lumps under the skin near the elbows, called rheumatoid nodules

How it is diagnosed

There is no single test. Dr. Jaffe puts together your history, a careful joint examination, bloodwork such as rheumatoid factor and anti CCP antibodies, markers of inflammation, and imaging done here in the office. Most patients leave the first visit with a clear plan for confirming the diagnosis.

Treatment

Treatment has one goal: to quiet the immune attack before it damages the joints, and to keep it quiet.

Step 01

Settle the flare

Short courses of anti inflammatory medication ease pain and swelling while longer acting treatment starts to work.

Step 02

Protect the joints

Disease modifying medication such as methotrexate, and biologics when needed, slow or stop the immune attack.

Step 03

Keep it quiet

Regular visits and bloodwork keep you safe on treatment. Some biologics are given in our own infusion suite.

Living with RA

A woman exercising

Movement helps. Gentle, regular exercise keeps joints mobile and muscles strong, and many patients find water exercise or tai chi easiest on sore joints.

Stopping smoking improves how well treatment works. We will talk through what is realistic for you, at your pace.

Clinical research

Patients with RA may qualify for studies of new treatments.

Dr. Jaffe is a Principal Investigator with GNP Research. Taking part is voluntary, and declining changes nothing about your care.

Visit gnpresearch.com ↗

Morning stiffness that lasts? Come in sooner.

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